Biological Control System and Modelling
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Follow on Instagram for UpdatesBiological Control System and Modelling Syllabus — Unit-wise Content
The official GTU curriculum for Biological Control System and Modelling (subject code ME01031051) as prescribed for BE · Semester 1 divides the course into 6 units, covering 33 listed topics. The unit-wise breakdown below is read from the GTU syllabus document for this subject code, so you can check what the course actually covers before deciding which papers to attempt.
Download the official syllabus PDF (ME01031051)Unit 1 Modelling of physiological system
- Introduction to physiological system
- classification of model – grey box & black box, parametric & non parametric
- lumped & distributed models
- linear & non-linear
- Purpose of physiological modelling and signal analysis
- Engineering system and physiological system
- System variables & properties
Unit 2 Time-Domain and Frequency Domain Analysis of Linear Control
- Systems descriptors of impulse and step responses
- open-loop versus closed-loop dynamics
- Simulink application: dynamics of neuromuscular
- reflex motion
- steady-state responses to sinusoidal inputs
- graphical representations of frequency response
- frequency response of a model of circulatory
- frequency response of glucose-insulin regulation
- Control of biological systems using biological parts
Unit 3 Identification of Physiological Control Systems
- Nonparametric and parametric identification methods
- problems in parameter estimation: identifiability and Input design
- identification of closed-loop systems: "opening the loop
- identification under closed-loop conditions
Unit 4 Optimization in Physiological Control
- Optimization in systems with negative feedback
- single-parameter optimization: control of Respiratory frequency
- constrained optimization: airflow pattern Regulation
- control of aortic flow Pulse
- adaptive control of physiological variables
Unit 5 Complex Dynamics in Physiological Control Systems
- Spontaneous variability
- nonlinear control systems with delayed feedback
- coupled nonlinear oscillators: model of circadian rhythms
- time-varying physiological closed-loop systems: Sleep apnea model
- propagation of system noise in feedback loops
Unit 6 Systems Biology of Diseases and the Design of Effective
- Treatments Introduction
- pathologies & control engineering perspectives
- engineering control systems & disease treatment
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