Unit 1 Optimization of Organic Reactions & Processes

12 lecture hours

• the purpose of chemical development
• discovering the best synthetic route
• Selecting the best route for scale-up
• Choice of raw materials
• reagents etc
• case studies
• the investigative approach to chemical development
• Effect of process variables on yield & quality of products
• Quality control in process analysis as an aid to optimization
• Designing a robust process & preventing scale-up problems
• Solvent effects
• Phase transfer catalyst
• chiral synthesis

Unit 2 Separation Techniques in Pharmaceutical Industry

6 lecture hours

• Separation (a) aspect of Chemical Purification & process separation technology (b)
• Introduction to Separation technology
• choosing a separation process
• Simulated moving bad (SMB) chromatography

Unit 3 Design , development of safe chemical process

6 lecture hours

• Development technologies for safe Process design
• Unit operations posing particular hazards during development
• Strategies for chemical hazards assessment
• Hazards of gas & vapor generation
• Identification of highly- energetic materials
• Process control considerations & safety critical systems

Unit 4 Nanoscience Technology

8 lecture hours

• classification of nanostructures and systems
• nanotechnology and pharmaceutical applications(Introduction) Nanoscale properties as a function of size: structural properties
• chemical properties
• mechanical properties
• thermal properties
• optical properties
• magnetic properties
• electronic properties

Unit 5 Fabrication methods(general approaches)

• bottom-up and templating approaches 8 Subject Code: 3173625 w.e.f
• AY 2018-19 Characterization methods- Imaging (microscopy) method
• analysis(spectroscopy) method
• size measurement etc

Unit 6 Gold and silver Nanoparticles

5 lecture hours

• properties and pharmaceutical/healthcare applications
• Molecular nanomaterials: dendrimers