Process Technology of Drugs & Intermediates
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Follow on Instagram for UpdatesProcess Technology of Drugs & Intermediates Syllabus — Unit-wise Content
The official GTU curriculum for Process Technology of Drugs & Intermediates (subject code 2173602) as prescribed for Chem. Tech. · Semester 7 divides the course into 5 units, covering 44 listed topics. The unit-wise breakdown below is read from the GTU syllabus document for this subject code, so you can check what the course actually covers before deciding which papers to attempt.
Download the official syllabus PDF (2173602)Unit 1 Raw materials
- Raw materials for Pharmaceutical Industry
Unit 2 Enzymes
- Enzymes as catalyst (a) in Synthesis for Pharmaceuticals (b) Introduction to Principle of enzymes catalyst
- Lipases & esterase are for hydrolytic conversion
- Lipases & esterase’s in organic solvents
- other hydrolytic reactions
- Enzyme- catalyzed C-X bond synthesis
- Enzyme-catalyzed reduction
- Chiral Technology
- Chemical Development of enantiomerically pure products
- chiral synthesis etc
Unit 3 Separation techniques in Pharmaceutical industry
- Separation (a) aspect of Chemical Purification & process separation technology (b)
- Introduction to Separation technology
- choosing a separation process
- Adsorption Separation methods
- Simulated moving bad (SMB) chromatography
- Large scale chromatography
- Heterogeneous catalyst & phase transfer catalyst
Unit 4 The Design & Development of Safe Chemical Processes
- the chemical process life-cycle
- Legislative requirements for safe process development & scale up, Development technologies for safe Process design
- Unit operations posing particular hazards during development
- Strategies for chemical hazards assessment
- Hazards of gas & vapor generation
- Identification of highly-energetic materials
- Small scale screening tests: case studies
- Flammability issues associated with chemical manufacture
- Gas & Vapor pressure systems
- Process control considerations & safety critical systems
- GMP in chemical development
Unit 5 Optimization of Organic Reactions & Processes
- Introduction the purpose of chemical development
- Discovering the best synthetic route
- Selecting the best route for scale-up
- Choice of raw materials
- reagents etc
- case studies
- the investigative approach to chemical development
- Effect of process variables on yield & quality of products
- Quality control in process analysis as an aid to optimization
- Designing a robust process & preventing scale-up problems
- Solvent effects
- Work up & product isolation
- Selecting the parameters to vary
- Planning for scale up, Design of environmentally friendly processes
- Effluent minimization & control
- Statistical methods of optimization
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