Introduction to Medicinal Chemistry & Biochemistry
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Follow on Instagram for UpdatesIntroduction to Medicinal Chemistry & Biochemistry Syllabus — Unit-wise Content
The official GTU curriculum for Introduction to Medicinal Chemistry & Biochemistry (subject code 2133601) as prescribed for Chem. Tech. · Semester 3 divides the course into 4 units, covering 34 listed topics. The unit-wise breakdown below is read from the GTU syllabus document for this subject code, so you can check what the course actually covers before deciding which papers to attempt.
Download the official syllabus PDF (2133601)Unit 1 Introduction to Medicinal & Pharmaceutical Chemistry
- Methods of classification of drugs based on structure & biological activity
- Concept of acidity & basicity of drugs &pKa values
- Introduction of absorption & distribution of drugs based on physicochemical properties
- Drug metabolism chemistry
Unit 2 Anti – infective
- Study of the chemistry of the following classes of drugs nomenclature
- SAR: - Anti-infective agents: antiseptic & disinfectant
- DHE antagonists
- antibiotics including stability & degradation products
- antiparasitic agents – antimalarial
- antimycobactrial agents
- antifungal agents
- anticancer agents
- diagnostic agents
- antiviral agents
- Non – steroidal anti – inflammatory agents
Unit 3 Cellular level cell & cell organelles
- Coenzymes & cofactors: role of vitamins as coenzymes
- Enzyme: structure
- mechanism of enzyme action
- enzyme kinetics
- enzyme inhibitors
Unit 4 Oxidative metabolism
- Biological oxidation
- respiratory cycle
- oxidation phosphorylation
- metabolism of carbohydrates: Photosynthesis
- pentose phosphate cycle
- TCA cycle
- Metabolism of proteins & amino acids
- urea cycle
- Metabolism of lipids: formation of fatty acids
- beta oxidation of fatty acids: DNA as carrier of genetic information
- transfers of information
- protein biosynthesis
- Miscellaneous: role of hormone & other body fluids
- importance general application in pharmaceutical industry concept of GMP
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